THE CURE INDEX
Helio Cure's evidence score based on human clinical trials for red light therapy.
A nerve injury is damage to a nerve that interrupts the signals it carries, which can bring pain, weakness, or numbness.
Only 3 human studies have looked at nerve injury, and across their 103 participants, they support red light therapy as effective. The CURE Index ranks this condition 71 out of 100, indicating strong confidence.
Across studies, the main gain reported after red light therapy was better muscle power.
2 of the 3 studies reported effective outcomes, and 1 found no significant benefit. Those 3 break down as 1 randomized controlled trial and 2 observational studies.
Session length is where these studies diverge most, from 30 seconds at one end to 300 minutes at the other, with treatment given in 1 to 24 sessions across 3 to 90 days. Of the wavelengths tested, 808 nm was most cited, in a band running from 632 to 904 nm.
EVIDENCE AT A GLANCE
The numbers behind the verdict.
MOST CITED WAVELENGTH
The wavelength appearing most often in studies that showed benefit for nerve injury.
808 nmTREATMENT PROTOCOL RANGES
The lowest and highest values used across nerve injury studies.
| PARAMETER | RANGE |
|---|---|
| Wavelength | 632-904 nm |
| Distance | Contact-15.8 inches |
| Session Frequency | 1-24 per week |
| Therapy Duration | 3-90 days |
3 Human Studies on Red Light Therapy for Nerve Injury
Muscle Power Improved More With Light After Nerve Injury Surgery
Comparing photobiomodulation (PBM) against no light treatment after nerve-transfer surgery, a 2020 randomized controlled trial examined recovery from an injury to the nerve network in the shoulder. 14 patients in Malaysia who had undergone surgery to reroute a working nerve and restore elbow bending were split into 2 equal groups, with 1 group receiving 808 nm light at 50 mW, 50 mW/cm², and 4 J/cm² in contact with the muscle at the front of the upper arm for 30 seconds per session, given daily on 10 consecutive weekdays. Average muscle power appeared higher in the group given PBM across 6 months of follow-up. No adverse effects followed the use of PBM.
- Study Type
- Randomized Controlled Trial
- Participants
- 14
- Treated Area
- Arm
- Wavelength(s)
- 808 nm
- Distance
- Contact
- Session Duration
- 30 seconds
- Session Frequency
- 10 per week
- Therapy Duration
- 10 days
- Study Scope
- Brachial Plexus Injury
Study Title: Photobiomodulation After Neurotization (Oberlin Procedure) in Brachial Plexus Injury: A Randomized Control Trial.
Arm Nerve Weakness Improved in 9 of 13 Patients After Laser
9 of 13 patients showed excellent improvement in a 2018 observational study of low-level laser therapy (LLLT) for weakness caused by injury to a nerve in the arm. The patients had developed the weakness from pressure on that nerve during awkward positioning and sleeping posture, and received 815 to 845 nm light at 1 W and 20.1 J/cm² for 30 seconds per session across 90 days, with muscle power in the wrist-lifting muscle graded by hand before and after treatment. According to the report, 4 of the 6 patients who also wore a brace showed excellent improvement. The report noted that maintaining the benefit depended on patients learning to avoid the postures that had caused the problem.
- Study Type
- Observational Study
- Participants
- 13
- Treated Area
- Arm
- Wavelength(s)
- 815-845 nm
- Distance
- Contact
- Session Duration
- 30 seconds
- Session Frequency
- 24 per week
- Therapy Duration
- 90 days
- Study Scope
- Peripheral Nerve Injury
Study Title: Low Level Laser Therapy for Radial Nerve Palsy Patients : Our Experience.
No Significant Benefit From Light Therapy in Jaw Nerve Injury
59% of patients reported feeling better after treatment in a 2025 observational study of photobiomodulation (PBM) for long-standing nerve injury in the jaw and tongue. 76 cases treated at a university clinic in Norway between 2007 and 2018 were examined, all involving nerve symptoms lasting more than 3 months, with 830 nm light delivered at 400 mW and doses between 13.3 and 40 J/cm², applied both inside and outside the mouth. The study found no statistically significant effect on those symptoms, and no link between the outcome and the patient's sex, the cause of the injury, which nerve was affected, how soon treatment began, or how many sessions were given. Because the study was retrospective and had no comparison group, the reported improvements could reflect placebo effects or the nerve recovering on its own.
- Study Type
- Observational Study
- Participants
- 76
- Treated Area
- Face/Jaw
- Wavelength(s)
- 830 nm
- Session Frequency
- 10-15 per week
- Study Scope
- Trigeminal Nerve Injury
Study Title: Efficacy of photobiomodulation therapy in managing iatrogenic trigeminal nerve injury: A retrospective case series.
The CURE Index (Clinical Understanding of Red-light Evidence) by Helio Cure is a 0-100 evidence score based on published human clinical trials. Higher scores mean stronger evidence. Read full methodology →
Data is powered by AI and reviewed by the Helio Cure team.
This page is for educational purposes only. Not medical advice. Consult a healthcare provider before starting red light therapy. Helio Cure does not diagnose, treat, or cure any medical condition.
Last updated: Sep 28, 2026

